GMP-Certified, ≥98% HPLC-Verified
FOXO4-DRI
Wholesale D-Retro-Inverso Senolytic Peptide. FOXO4-DRI (also known as Proxofim) is a synthetic D-retro-inverso peptide derived from the p53-interaction domain of FOXO4, engineered with a reversed sequence and D-amino acid substitutions for enhanced stability. It is widely researched in cellular senescence and longevity science.
≥98% HPLC-VerifiedGMP & ISO 9001:2015 certifiedCOA with every batch
GMP · ISO · HACCPUK & Berlin manufacturingThird-party testedManufacturer direct since 2018
Compound specifications
FOXO4-DRI at a glance
| Compound Name | FOXO4-DRI |
| Alternative Name | Proxofim, FOXO4-D-Retro-Inverso |
| Classification | Senolytic peptide, FOXO4-p53 interaction blocker |
| Peptide Type | Synthetic D-retro-inverso peptide |
| CAS Number | 2460055-10-9 |
| Molecular Formula | C228H388N86O64 |
| Molecular Weight | Approximately 5358.15 g/mol (free base) |
| Structure | D-retro-inverso peptide comprising part of the p53-interaction domain of FOXO4, with a reversed amino acid sequence and D-amino acid substitutions for resistance to enzymatic degradation |
| Purity | ≥98% (HPLC-verified, batch-by-batch) |
| Format | Lyophilised peptide powder, multi-dose research vials |
| Appearance | White to off-white lyophilised powder prior to reconstitution |
| Solubility | Reconstitute using bacteriostatic water or sterile laboratory-grade water |
Note: Molecular weight figures may differ depending on whether the free base or acetate salt form is supplied. Please confirm with our team which form is reflected in the batch Certificate of Analysis.
Ordering
Available Strengths
FOXO4-DRI is available wholesale in the following strength:
FOXO4-DRI 5mg
Available for bulk ordering with flexible MOQs. Private label packaging and labelling is available for qualifying buyers — see our Private Label page for details. If you require additional strengths for your order, contact us to discuss availability.
Quality & documentation
Quality Assurance
Every batch of FOXO4-DRI supplied by Peptide Direct meets the same standard as our full compound range:
- GMP certified manufacturing conditions
- ISO 9001:2015 certified quality management
- HPLC purity verification to ≥98%, batch-by-batch
- Certificate of Analysis supplied with every order
Wholesale
Wholesale Information
FOXO4-DRI is available through Peptide Direct for:
- Wholesale peptide supply
- International distribution
- Commercial wellness partnerships
- Private label solutions
Storage & handling
Storage Information
Store refrigerated at 2–8°C in a cool, dry environment away from direct light. For long-term storage prior to reconstitution, freezing conditions are recommended. Storage conditions are confirmed on the Certificate of Analysis supplied with each order.
Request a wholesale FOXO4-DRI quote
Tell us the strength and quantity you need. We reply within 24 hours with tiered pricing and a current batch COA on request. COAs, pricing and samples available — B2B enquiries only.
Frequently asked questions
What is FOXO4-DRI?
FOXO4-DRI (also known as Proxofim) is a synthetic D-retro-inverso peptide derived from the p53-interaction domain of FOXO4, engineered with a reversed sequence and D-amino acid substitutions for enhanced stability. It is widely researched in cellular senescence and longevity science.
What does "D-retro-inverso" mean?
A D-retro-inverso peptide has its amino acid sequence reversed and all standard L-amino acids replaced with their mirror-image D-amino acid counterparts. This structural modification increases resistance to enzymatic breakdown, extending the peptide's stability while maintaining its functional properties.
What purity does Peptide Direct's FOXO4-DRI meet?
All FOXO4-DRI supplied by Peptide Direct is verified by HPLC analysis to a minimum purity of ≥98% on a batch-by-batch basis, with a Certificate of Analysis supplied on every order.
What strengths are available?
FOXO4-DRI is available wholesale in 5mg, with flexible minimum order quantities for bulk buyers. Contact us if you require other strengths.
Can I get FOXO4-DRI under my own brand?
Yes. Private label packaging, vials, and labelling are available for qualifying wholesale buyers. See our Private Label page for details.
How should FOXO4-DRI be stored?
Store refrigerated at 2–8°C, away from direct light. For long-term storage, freezing conditions are recommended prior to reconstitution.
Is FOXO4-DRI manufactured under GMP conditions?
Yes. All FOXO4-DRI supplied by Peptide Direct is manufactured under GMP and ISO 9001:2015 certified conditions, the same standard applied across our full compound range.
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For research and laboratory purposes only. Not intended for human consumption, medical use, diagnosis, treatment, cure, or prevention of any disease. Products sold by Peptide Direct are intended exclusively for qualified research professionals and licensed institutions. Buyers are responsible for ensuring compliance with all applicable laws and regulations within their jurisdiction.